Pediatric Tables:

Indrit Reso, MD April 2003

Antibiotics 
Resuscitation Drugs
IV Fluid Composition
Other Pediatric Drugs & Data

STAT Drugs from MMC Pharmacy

Antibiotics: 
    These are DAILY doses: adjust accordingly

Antibiotic

Age 0-7 days

Age 8-28 days

Age > 28 days

Ampicillin

100-200 mg/kg/day, q 12 h

200 mg/kg/day; q 8 h

200-300 mg/kg/day, q4-6h

Cefotaxime

100 mg/kg/day, q 12 h

150 mg/kg/day; q 6-8 h

200 mg/kg/day, q 6 h

Ceftriaxone

Not for neonate

50-75 mg/kg/day, q12h

Cefuroxime

Not for neonate

200 mg/kg/day,  6-8 h

Cefazolin

40 mg/kg/day, q12h

60 mg/kg/day; q 8h

50-100 mg/kg, q8h, up to 3 grams

Gentamicin

5 mg/kg/day, q12h

5-7.5 mg/kg/day; q 8h

6 mg/kg/day, q8h

Clindamycin
(IV over 30')

<1 mo. 15 mg/kg/day; q12h

>1 mo. 20 mg/kg/day, q12h

Nafcillin

50 mg/kg/day, q12h

100 mg/kg/day; q 6-8h

200 mg/kg/day, q4-6 h

Penicillin G

100,000U/kg/day, q12h

200,000 U/kg/day; q 6-8h

300,000 U/kg/day, q4-6h

Ticarcillin

150 mg/kg/day, q12h

200-300 mg/kg/day; q 6-8h

300-400 mg/kg/day, q4-6h

Tobramycin

4 mg/kg/day, q12h

6 mg/kg/day; q 8h

6 mg/kg/day, q8h

Vancomycin
(IV over 1h)

20-30 mg/kg/day, q12h

30-45 mg/kg/day;  q 8h

30-45 mg/kg/day, q8h

 

 

Resuscitation Drugs:

Drug Bolus

Conc.

Dose

Epinephrine

1 mg + 9 ml NS = 1:10.000 (100mcg/cc)

10 mcg/kg (0.1 ml)/kg

Na+ Bicarbonate

1 mEq/ml

1-2 mEq (1-2 ml)/kg

Atropine

1 mg/ml; also  0.4mg/ml

0.02 mg/kg

Ca+ Chloride

100 mg/ml (10%)

5 mg (0.05 ml)/kg

Ca++ Gluconate

100 mg/ml (10%)

15 mg (0.15 ml)/kg

Lidocaine

20 mg/ml (2%)

1 mg (0.05 ml)/kg

Adenosine

0.05 mg/kg rapid IV push, increase by 0.05 increments, (0.1, 0.15, 0.02, 0.25,) mg/kg; max 12 mg

Infusions

Preparation
(**HIGHLY CONCENTRATED**)

Dose

Epinephrine

Mix: 0.6 mg x wt (kg) in 100 ml D5W
Rate: 1 ml/hr = 0.1 mcg/kg/min

0.1-1 mcg/kg/min

Isoproterenol

Mix: 0.6 mg x wt (kg) in 100 ml D5W
Rate: 1 ml/hr = 0.1 mcg/kg/min

0.1-1 mcg/kg/min

Dopamine

Mix: 6 mg x wt (kg) in 100 ml D5W
Rate: 1 ml/hr = 1 mcg/kg/min

2-20 mcg/kg/min

Dobutamine

Mix: 6 mg x wt (kg) in 100 ml D5W
Rate: 1 ml/hr = 1 mcg/kg/min

2-20 mcg/kg/min

Milrinone

Premixed from Pharmacy: 200mcg/cc

Load: 50mcg/kg over 15-20'
Maintenance: 0.5mcg/kg/min

Composition of intravenous crystalloid solutions:

Solution
(pH, osmolarity)

Na+
mEq/l

K+
mEq/l

Cl-
mEq/l

Lactate
mEq/l

Ca++
mEq/l

Glucose
mg/dl

5% Dextrose
(5.5, 253)

_

_

_

_

_

500

Ringer's
(6.0, 309)

147

4

155

_

4

_

Lac. Ringer's
(6.7, 273)

130

4

109

28

3

_

D5/Lac. Ringer's
(5.3, 527)

130

4

109

28

3

500

D5 0.22% NS
(4.4, 330)

38.5

_

38.5

_

_

500

D5/ 0.45% NS
(4.2, 407)

77

_

77

_

_

500

0.9% NS
(5.7, 308)

154

_

154

_

_

_

Normosol R
(7.4, 295)

140

5

98

Acetate 27
Gluconate 23

_

_

**************************************************

Ordering STAT Drugs from Maine Med Pharmacy

1. Call Pharmacy Stat Line x3333
2. Give patient name, drug, and location for delivery
3. Enter order in SCM when you are able.

Examples: norepinephrine drip, bivalirudin, dantrolene (mixed)